Engineered for Bone Regeneration
Thermoresponsive Injectable Hydrogel for Promoting Osteoblast Activity (Available for Licensing in Any Country)
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Sector: MEDICAL, Origin: INDIA
Bone defects from trauma, tumours, or diseases need biocompatible scaffolds for regeneration. Existing grafts have limitations, highlighting the need for an injectable, thermoresponsive, and biodegradable scaffold that supports bone growth, angiogenesis, and innervation.
The present invention relates to an injectable, thermoresponsive and biodegradable hydrogel formulated from mucoadhesive proteins, that enhances osteoblast activity, angiogenesis, mineralization, and innervation to support bone formation. It also provides a method for preparing the hydrogel and enables incorporation of growth factors for improved bone regeneration
Key Highlights:
- Exists in solution form at room temperature and gels in situ upon reaching body temperature, making it ideal for minimally invasive delivery.
- Mucoadhesive Protein-Based Composition providing natural adhesion, biocompatibility, and cell signalling support.
- Promotes blood vessel and nerve formation, essential for functional bone regeneration.
- Enhances bone mineralisation and allows incorporation of growth factors for targeted healing.
Patent:
Indian Patent Filed ( 202331020916 )
Development Stage:
TRL – 3
Seeking:
Available for Licensing or for Collaboration in any BRICS+. Country
- Expansion to International market through collaboration with Government/Private hospitals
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